pentobarbital decreases levels of atrasentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration with sturdy or moderate CYP3A inducers is anticipated to reduce atrasentan systemic publicity, which may lessen efficacy. .
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pentobarbital will lessen the level or impact of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. The efficacy of hormonal contraceptives can be diminished.
pentobarbital will reduce the extent or impact of aripiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lower the level or impact of saxagliptin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital will lower the extent or result of ramelteon by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.
pentobarbital will minimize the extent or impact of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Influence of coadministering a robust CYP3A4 inducer with fedratinib has not been analyzed.
pentobarbital will lower the extent or outcome of rabeprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.
pentobarbital will lessen the level or result of methadone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital raises toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. CYP3A4 inducers may perhaps enhance the metabolism of ifosfamide to its Energetic alkylating metabolites.
pentobarbital will lower the extent or influence of isavuconazonium sulfate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the level or influence of acalabrutinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Keep track of Intently (1)pentobarbital will decrease the extent or result of buprenorphine subdermal implant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Check patients by now on buprenorphine subdermal implant who need freshly-initiated procedure with CYP3A4 戊巴比妥鈉製作 inducer for indications and symptoms of withdrawal. If your dose of the concomitant CYP3A4 inducer can not be decreased or discontinued, implant elimination can be necessary along with the affected individual really should then be treated with a buprenorphine dosage type that permits dose changes.
pentobarbital will lower the extent or impact of montelukast by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Not known.